Frommer's Review
This virtually legendary bar hosts comedy clubs 3 nights a week: Thursdays and Saturdays, it's Murphy's International Comedy Club, and Wednesdays, it's the Comedy Cellar (which, you'll be unsurprised to learn, is held upstairs). While Murphy's International has more established comedians, the Cellar has the young and unpredictable ones.
Note: This information was accurate when it was published, but can change without
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planning your trip.