One of Chile's best-known city markets, La Recova, lies on the square at the corner of Prat and Cienfuegos just 3 blocks from the plaza. Many of the handicrafts are pretty tacky and most feature goods imported from Peru or Bolivia, but sample some of the local sweets and liquors for an authentic taste of the area. You'll also find items in lapis lazuli and combarbalite, a unique, gray-green semi-precious stone found only around Combarbalá, a village to the south. In January and February, it's open Monday through Saturday from 10am to 10pm and Sunday from 10am to 5pm; during the rest of the year, Monday through Saturday from 10am to 9pm, and Sunday from 10am to 3pm.
Downtown, the main shopping area includes Cordovez and Prat streets departing from the plaza. A shopping mall straddles La Serena's colonial center to the south next to the bus station, while a large strip mall lies to its west just across the train tracks, each keeping the neocolonial style and each featuring retail chains common in Chile, including clothing and athletic goods stores. The large supermarket and hardware store on the strip mall make them convenient for stocking up on food or camping equipment. They also offer some electronics, as do several stores in the downtown shopping district selling supplies such as memory cards for cameras and cellphone batteries.