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Open to all ages, this club’s 280-seat main stage is an intimate space to see some well-known performers—the Cowboy Junkies and Jackson Browne have played here in 2014, and Sarah Silverman is a regular—within an adventurous lineup of rock, cabaret, theater, comedy, and spoken word. Check the website to catch resident musician, songwriter and producer Jon Brion’s awe-inspiring monthly one-man show, which involves playing numerous instruments simultaneously and composing songs on the spot from titles tossed out by the audience.