Annapolis Inn (Annapolis, Md.; tel. 410/295-5200): This sumptuous Georgian-style house was originally the home of Thomas Jefferson's physician in the 1770s. A three-course breakfast is served on fine china in the cranberry-red dining room. Selling points include Jacuzzis, a room with its own deck, a patio surrounding a koi fishpond, and experienced, welcoming hosts.
Tilghman Island Inn (Tilghman, Md.; tel. 800/866-2141): Waterfront rooms take full advantage of the inn's setting on Knapps Narrows on the Eastern Shore. The bedrooms are spacious, the amenities are comfy, and the welcome is warm.
Waterloo Country Inn (Princess Anne, outside Crisfield, Md.; tel. 410/651-0883): This 1775 Georgian manor on Maryland's Eastern Shore sits right on the banks of Monie Creek. It offers seclusion, peace, and tranquillity, whether you're wandering the grounds, canoeing the lovely tidal creek, or biking the back roads of Somerset County.
Inn at Osprey Point (Rock Hall, Md.; tel. 410/639-2194): Who can resist a room with a view? This modern Eastern Shore inn has plenty of charm in its individually designed guest rooms. Amenities include an acclaimed restaurant, a pool, a marina, and those views of the Chesapeake Bay.
Stonebow Inn (Grantsville, near Deep Creek Lake, Md.; tel. 800/272-4090): Location makes the Stonebow, a restored 1877 Victorian, a good bet. It's right on the Casselman River beside the Spruce Forest Artisan Village, a few minutes from Deep Creek Lake and as far from the hustle and bustle as you want to be.
Lighthouse Club Hotel (Ocean City, Md.; tel. 800/371-5400): This hotel was designed for romantic beach getaways. Leave the kids at home and come here for secluded luxury with a view of the bay. Some rooms have fireplaces and Jacuzzis, too.