The landmark Omni William Penn, 530 William Penn Place (tel. 888/444-6664 or 421/281-7100; www.omniwilliampenn.com), is Pittsburgh's historic grande dame. Most guests at this downtown hotel are drawn to the crystalline lobby and the romantic, luxurious guest rooms. Rates start at $169 double. Another romantic downtown favorite is the Renaissance Pittsburgh Hotel, 107 6th St. (tel. 866/454-4400 or 412/562-1200; www.renaissancepittsburgh.com), a 14-story copper-clad hotel known for its 30-foot glass atrium, marble lobby, upscale rooms, and fabulous views. Doubles begin at $199. A $12-million renovation and a great location attract business and leisure travelers to the Doubletree Hotel, 1 Bigelow Sq. (tel. 800/225-5858 or 412/281-5800; www.doubletree.com), adjacent to Mellon Arena and within blocks of the David Lawrence Convention Center. Doubles begin at $139. The Holiday Inn Select, 100 Lytton Ave. (tel. 888/465-4329 or 412/682-6200), with doubles starting at $149, offers pleasant affordable accommodations within blocks of Carnegie Mellon, the University of Pittsburgh, and the Carnegie Museums of Art and Natural History.