Christopher Columbus became the first European to land on the shores of Puerto Rico, on November 19, 1493, near what would become the town of Aguadilla, during his second voyage to the New World. Giving the island the name San Juan Bautista, he sailed on in search of shores with more obvious riches for the taking. A European foothold on the island was established in 1508, when Juan Ponce de León, the first governor of Puerto Rico, imported colonists from the nearby island of Hispaniola. They founded the town of Caparra, which lay close to the site of present-day San Juan. The town was almost immediately wracked with internal power struggles among the Spanish settlers, who pressed the native peoples into servitude, evangelized them, and frantically sought for gold, thus quickly changing the face of the island.
Meanwhile, the Amerindians began dying at an alarming rate, victims of imported diseases such as smallpox and whooping cough, against which they had no biological immunity. The natives paid the Spanish back, giving them diseases such as syphilis against which they had little immunity. Both communities reeled, disoriented from their contact with one another. In 1511 the Amerindians rebelled against attempts by the Spanish to enslave them. The rebellion was brutally suppressed by the Spanish forces of Ponce de León, whose muskets and firearms were vastly superior to the hatchets and arrows of the native peoples. In desperation, the Taínos joined forces with their traditional enemies, the Caribs, but even that union did little to check the growth of European power.
Because the Indians languished in slavery, sometimes preferring mass suicide to imprisonment, their work in the fields and mines of Puerto Rico was soon taken over by Africans who were imported by Spanish, Danish, Portuguese, British, and American slavers.
By 1521 the island had been renamed Puerto Rico ("Rich Port") and was one of the most strategic islands in the Caribbean, which was increasingly viewed as a Spanish sea. Officials of the Spanish Crown dubbed the island "the strongest foothold of Spain in America" and hastened to strengthen the already impressive bulwarks surrounding the city of San Juan.