Because Sucre is crawling with young university students, there are tons of charming bars near Plaza 25 de Mayo, especially on Calle N. Ortiz leading away from the square. I recommend the Joy Ride Café & Bar, Calle N. Ortiz 14 (tel. 0104/6425-544; www.joyridebol.com), owned by a Dutch guy and serving good beer and excellent light meals. This is where many gringos spend the evening and sign up for one of their biking or hiking tours. Next door, Picadilly is another popular bar that also serves Indonesian food. If you fancy mojitos with a Bolivian twist -- coca leaf -- go to Locots, Bolivar 465 (tel. 6915958). Another good bar with both locals and foreigners is Kultur Café Berlin, Calle Avaroa 326 (tel. 6424521). If you're looking to dance, try Mitos (no phone), Calle Francisco Cerro at the corner of Calle Loyaza; and Tío Lalo (no phone), Calle San Alberto 680. Note that most everything is eerily quiet during the week; the above bars and clubs, with the exception of Joy Ride, are open only Wednesday through Saturday.
