This elegant 13th-century palace houses Sicilian works from the Middle Ages through the 20th century, including Antonello da Messina’s “Annunciation” (1474). The artist’s remarkable attention to detail is evident: Tall windows, beams, columns, the Virgin’s bed, and a blue-and-white vase compose an intricately rendered interior, with bright light infusing the spaces. The scene is typical of the Flemish paintings that were popular in Naples, where Messina studied after leaving his native Sicily as a teenager.