The nearest airport is 65 miles to the west at Panama City Beach. From there, you'll have to rent a car or take an expensive taxi ride. The Tallahassee Regional Airport is about 85 miles to the northeast.
The scenic way to drive here is via the Gulf-hugging U.S. 98 from Panama City Beach, or via U.S. 319 and U.S. 98 from Tallahassee. From I-10, take exit 142 at Marianna, then follow Florida 71 south to Port St. Joe; from there, take U.S. 98 East to Apalachicola.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.