After crossing either the Bourne or Sagamore bridge, head east on Route 6 or 6A. The Sagamore Bridge will get you closer to your destination. Route 6A passes through West Barnstable and Barnstable Village; exit 6 (Rte. 132) off Route 6 leads to Hyannis.
You can fly into Hyannis's Barnstable Municipal Airport, and there is good bus service from Boston.
The Sealine (tel. 800/352-7155) makes a circuit of Barnstable, Mashpee, and Falmouth, Monday through Saturday, and the fare is a reasonable $1 to $4 (depending on the distance); children 5 and under ride free. The Hyannis Area Trolley (tel. 800/352-7155 or 508/385-1430) covers two loops -- the Route 132 malls and the Main Street/waterfront area -- every half-hour from 10am to 9pm from late June to early September. Rates are $1 for adults, 50¢ for seniors, and free for children 5 and under.
For information contact the Hyannis Area Chamber of Commerce, 397 Main St., Hyannis, MA 02601 (tel. 508/775-2201; fax 508/775-7131; www.hyannis.com), which is open Monday through Saturday 9am to 5pm, Sunday 10am to 2pm. The handsome chamber building on Main Street, which used to be the town hall, also contains the John F. Kennedy Hyannis Museum and the Cape Cod Baseball League Hall of Fame. The Cape Cod Chamber of Commerce, routes 6 and 132 (just off the exit 6 eastbound ramp), Centerville, MA 02632 (tel. 888/332-2732 or 508/362-3225; fax 508/362-2156; www.capecodchamber.org), is open year-round: mid-April to mid-November daily 9am to 5pm, and mid-November to mid-April Monday through Saturday 10am to 4pm.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.