The city’s first skyscraper, the Ames Building opened in 1893 and became a hotel in 2007. It’s an unusual place, with an uber-traditional Richardsonian Romanesque exterior and a stripped-down interior that contrasts invitingly with the comfy-cozy beds. Wood floors—again, unusual—sleek furnishings, and the predominantly white-and-gray color scheme add to the minimalist feel of the guest rooms, which are laid out in 11 different configurations. Vistas from the higher floors are sensational; rooms facing State Street have oblique water views.