This hotel in Buffalo, Wyoming offers an indoor pool with hot tub and a gym. The hotel is located off Interstate 25 and Big Horn National Forest is 10.5-miles away. Each guest room at the Hampton Inn & Suites Buffalo is furnished with a microwave, a refrigerator and coffee facilities. Cable TV is also available in every room. Buffalo Hampton Inn & Suites is 12.3-miles from lake De Smet. The hotel is located halfway between Mount Rushmore and Yellowstone National Park.