Olympic Airways offers at least three flights daily to and from Athens in high season. (Flight time is about 50 min.) Flights to Chania from other points in Greece go through Athens. Aegean Airlines also offers several flights daily to and from Athens. The airport is 15km (10 miles) out of town on the Akrotiri. Public buses meet all flights except the last one at night, but almost everyone takes a taxi (about 20€).
One ship makes the 10-hour trip daily between Piraeus and Chania, usually leaving early in the evening (www.ferries.gr). During tourist season Hellenic Seaways runs a once-daily high-speed catamaran between Piraeus and Chania that cuts the trip down to about 5 hours (www.greekislands.gr). All ships arrive at and depart from Soudha, a 20-minute bus ride from the stop outside the municipal market. Many travel agents around town sell tickets. In high season, if you're traveling with a car, make reservations in advance, or check with the Paleologos Agency (www.ferries.gr).
Buses run almost hourly from early in the morning until about 10:30pm, depending on the season, connecting Chania to Rethymnon and Iraklion. (Round-trip fare to Iraklion for example, is 25€.) There are less frequent, and often inconveniently timed, buses between destinations in western Crete. The main bus station to points all over Crete is at 25 Kidonias (tel. 28210/93-306). Get there plenty early -- it can be a madhouse in high season!
All the usual agencies can be found in the center of town, but I've always had reasonable and reliable service with Europrent, at 87 Halidon (tel. 28210/27-810; www.europrent.gr).
It should be noted that in July 2009, the taxi drivers of Chania agreed to observe the posting of standard fares to some of the most frequented destinations in and around the city's center (such as the airport or points on the Akrotiri, or from one edge of the city to the other). These posting are supposed to be visible at major taxi pickup points, and although the actual charge cannot always be held to the exact penny (due, say, to traffic conditions that cause long waits), these posted costs should be useful in an appeal to the Tourist Police if you feel you have been grossly overcharged. Don't forget that taxi drivers are allowed a number of surcharges -- late at night, extra luggage, and so on.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.