This handsome wooden mansion was built around 1853 by the wealthy Lucas family, was restored in the 1990s, and is now a friendly B&B oozing Southern hospitality. Breakfasts are excellent (think orange-glazed croissant French toast), and the Charleston tradition of late afternoon wine, cheese, and crackers (at 4pm) is nicely done here. Rooms are furnished with original heart-pine floors, antiques, and four-poster and canopied beds. Three rooms are located in the nearby Guest House, built around 1850 as the carriage house for Wickliffe House (now a wedding venue and Tea Room). Cannonboro is located on the west side of Downtown, between the Medical School and the College of Charleston, but only a brisk walk from the Historic District.