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Tucked inside the super hip Acme Hotel, The Berkshire Room is one of the more mellow bars in the River North area. Dim and casual, but not dive-ish in the slightest, you can get just about any libation you can think of, from inexpensive beers, including a section designated to “Blue Collar Lagers,” like Miller Lite, to “Dealer’s Choice” cocktails, wherein you select the spirit (mezcal, sake, blended Scotch, wheated bourbon, and many more) the flavor profile (sweet and sour, fruity, herbaceous, strong and stirred, spicy, smoky), and even the glassware. Although new to the scene, the bar is drawing in large numbers of locals, which is quite a feat for a River North hotel bar.