Choluteca sits just off the Pan-American Highway. Buses depart from the main terminal on Boulevard Carranza and 3a Avenida NE, and several private terminals across the street. Transportes Mi Esperanza (tel. 504/2882-2712) runs buses to and from Tegucigalpa (L65; 3 1/2 hr.) from 4am to 6pm, including four ejectivo departures. For San Pedro Sula or the North Coast, transfer at Tegucigalpa.
Border Crossings: El Triunfo/Guasaule
Direct buses serve the 45-minute ride (L30) to the border town of El Triunfo and its Nicaraguan counterpart, Guasaule, every half hour during daylight from the main terminal in Choluteca. Buses are waiting on the other side for connections to León and Grenada. This is one of the seedier border crossings in the country, so keep an eye on your belongings at all times and be on the lookout for pickpockets.
Border Crossing: El Amatillo/San Carlos
El Amatillo, on the border with El Salvador, can be reached either from Choluteca (L40; 2 hr.) or Tegucigalpa (L60; 3 hr.). Buses leave during the day every 30 minutes or so in both directions for both cities. The crossing is fairly straightforward; however, it tends to be dreadfully slow, and lines tend to be long. There is connecting transport on the other side to San Salvador and elsewhere in El Salvador.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.