The Pyramids in Giza (Giza): There's no way to come to Egypt and not visit the pyramids. They are as vast and imposing as they were when they were built more than 4 millennia ago, and their impact has not been dimmed by the crowds of tourists and touts.
Valley of the Kings (Luxor): Since it was first excavated at the beginning of the 20th century, this steep-sided valley on the west bank in Luxor has long been drawing tourists to its underground complex of richly decorated tombs. There is now a whole industry built on these visitors, and rightly so -- it's a must-see.
Sound and Light Show at Karnak Temple (Luxor): Justly famous for its massive hypostyle hall, this vast temple complex reveals a whole new side of itself at night. Follow the narration through the ancient courtyards, and try to snap a picture of the dramatic lighting effects.
Medinet Habu (West Bank): This often overlooked temple has it all: big walls, glorious gory hieroglyphs, and a great rural setting -- and with far less hassle than you get almost everywhere else in Upper Egypt.
Temple of Amun (Siwa): This small, remote temple in the distant western desert oasis is plain and not very well preserved compared to the sites of Luxor and the Giza Plateau, but it does have unparalleled mystique.
Saqqara: The setting makes this site even more special than its historical significance. Like the pyramids in Giza, it sits on the edge of the desert looking down at the river valley. Whereas the megalopolis of Cairo sits at the foot of the monument at Giza, Saqqara is surrounded by greenery and looks like it might have many millennia ago.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.