The streets outside are busy 24/7, but you’d never know it from the perfume-scented calm of these upper-floor rooms in a building where Romantic poet Percy Shelley once lodged. Bedrooms are midsize and mix contemporary details—laminate floors and soft, thick mattresses—with baroque flourishes like gilded picture frames and artfully distressed furniture. This is far from the sexiest location in town, but it’s much improved in recent years, has unbeatable transportation links, and is only 5 minutes’ walk from the Duomo steps. An optional Italian breakfast is served at a cafe opposite the Medici Chapels.