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Decor in this former noble Florentine family home retains its authentic palazzo feel, though carpets have been added for comfort and warmth. No two rooms are the same—stone walls this thick cannot just be knocked through—and several have antiques integrated into their individual schemes. Grand rooms at the front (especially 101, 118, and 228) have spectacular Renaissance-coffered ceilings and masses of space. Bathrooms are plainer by comparison. Sleep at the back or looking onto the internal courtyard and you’ll wake to an unusual sound in Florence: birdsong. The adjacent bistro, Il Desco, is under the same ownership and serves seasonal Mediterranean dishes made with organic ingredients; its open to guests and nonguests alike (lunch only Oct–Easter).