Lecce is connected to Brindisi by hourly train service on the state-run FS line. For service from points east and south, you'll have to take the FSE line, which isn't known for its speed. Several trains coming from Gallipoli enter Lecce each day. The train station is about 2km (1 1/4 miles) from Piazza Sant'Oronzo, in the center of the old quarter. Call tel. 892021 in Italy for schedules and information.
If you have a car, take Route 613 from Brindisi.
The tourist office is at Via Vittorio Emanuele 24 (tel. 0832-332463; www.pugliaturismo.com), open Monday, Wednesday, and Friday from 8am to 2pm, Tuesday and Thursday 3 to 6pm.