Most folks visit Los Llanos as part of a package tour out of either Mérida or Caracas. In this case, your transportation will be taken care of. It is possible to reach the gates, or at the least, nearby towns of most of the hatos by bus as well, but since you have to coordinate your arrival time and pickup with the lodge, it is best that you work out any independent travel closely with the lodge beforehand.
Note: It's hot in Los Llanos year-round, and in the dry season, the sun can be downright brutal. Definitely bring sunscreen, but also make sure that you've got a wide-brimmed hat. Mosquitoes and other insects can also be plentiful here. Although repellent is recommended, I often prefer using lightweight long-sleeved shirts and pants. Also, be sure to bring glasses or sunglasses on the safari-style tours. When the trucks pick up a bit of velocity, particularly around dusk or on the night tours, you'll find your corneas attract insects like a semi's windshield.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.