This itinerary offers a great deal of contrast by starting in the resort area of Los Cabos. After immersing yourself in any number of seaside activities, take a short tour of southern Baja that includes bohemian Todos Santos before crossing the Sea of Cortez and boarding a train that climbs up through rugged Sierra Tarahumara, hugging the sides of the Copper Canyon. Stop here to enjoy the beautiful serenity, and then reboard the train heading to Chihuahua, once home to Pancho Villa.

Days 1, 2 & 3: Cabo San Lucas, San José del Cabo & Todos Santos 

Take your time enjoying the gorgeous setting of these resort towns and the wide-ranging activities they offer. Rent a car to drive along the coast, and perhaps visit the town of Todos Santos for a feel of the region's character.

Day 4: La Paz to Los Mochis

Take a bus or colectivo to La Paz and, from there, to the ferry dock. After a 5-hour voyage, you'll arrive at Topolobampo, the port area of Los Mochis.

Days 5 & 6: Bahuichivo & Cerocahui 

The train departs early in the morning and, by late morning, is snaking its way through some of the most beautiful canyon land on the trip. By midday, you reach Bahuichivo, where you can get transportation to the town and mission of Cerocahui. This is an excellent place for hiking, horseback riding, and driving tours to the overlook of Cerro Gallego.

Days 7 & 8: Creel 

Continue by train to Creel, where a car can then take you to the nearby Copper Canyon Sierra Lodge. Here you can enjoy the peace and quiet of the sierra, visit an old mission, hike to a nearby waterfall, and meet Tarahumara Indian women, who come to sell their pine-needle baskets and other handicrafts.

Days 9 & 10: Chihuahua 

You'll arrive at night. Use part of the next day to wander the historic downtown area and visit Pancho Villa's house before flying back home.

Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.