Four Seasons Hotel Prague (Veleslavínova 2a, Prague 1; tel. 221-427-000): Arguably the number-one luxury hotel in Old Town, with many rooms having a river view of Prague Castle and Charles Bridge. The house restaurant, Allegro, has won a Michelin star 2 years running, a first in all of central Europe.
Hotel Savoy (Keplerova 6, Prague 1; tel. 224-302-430): This opulent but tasteful small hotel suggests London more than Prague. Enjoy afternoon tea in the library, where you can read by a crackling fire.
Hotel Paríz (U Obecního domu 1, Prague 1; tel. 222-195-195): This restored Art Nouveau hotel recalls 1920s Prague, one of the wealthiest cities on earth at that time. It's across from another remodeled gem, the Municipal House (Obecní dum).
Hotel Aria (Trziste 9, Prague 1; tel. 225-334-111): This reconverted baroque townhouse plays on Prague's musical heritage, with each one of its beautifully appointed rooms named after a composer or performer. Some rooms look out over the Vrtbovská garden. Don't leave without having dinner or a drink on the rooftop terrace.
Hotel Josef (Rybná 20, Prague 1; tel. 221-700-111): For fans of clean lines, white walls, and minimalist chic, the Josef was Prague's first real boutique hotel and still arguably the best.
Hotel Mandarin Oriental (Nebovidská 1, Prague 1; tel. 233-088-888): This local branch of the international luxury chain occupies a sublime location in a converted monastery in a quiet corner of Malá Strana. This is no cookie-cutter chain; each room is funky and wonderful in its own unique way.
U zlaté studne (U zlaté studne 4; tel. 257-011-213): This reconstructed 17th-century townhouse sits just below Prague Castle, and many of the rooms afford stunning views out over Malá Strana and Old Town. Rumors were swirling in April 2009 during U.S. President Barack Obama's visit to Prague that he and Mrs. Obama were going to dine on the restaurant's terrace. He ended up staying (and eating) at the Hilton, but this would have been a more presidential choice.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.