By Plane -- LAN Airlines (tel. 600/526-2000; www.lan.com) serves Osorno's Aeródromo Cañal Bajo (ZOS; tel. 64/247555), with two daily flights from Santiago; one flight stops first in Temuco. Osorno is a 1-hour drive from Puyehue. LAN has more frequent flights from Santiago to Puerto Montt, a 2-hour drive from Puyehue.
By Bus -- Bus service from Osorno is provided by Buses Puyehue, with almost hourly trips to and from Puyehue, departing from the Terminal de Buses Rurales at Errázuriz 1300 (tel. 64/201237). From Bariloche, Argentina, Andes Mar and Río de la Plata buses head to Osorno and stop along the highway near Puyehue or directly at the Hotel Termas de Puyehue. If you're trying to get to Puyehue from Puerto Montt, you'll need to transfer at Osorno. From Santiago, the buses run by Tas Choapa (to Bariloche) depart Monday, Wednesday, and Friday, heading for Bariloche; they'll drop you off in Puyehue. From Puerto Varas, an excellent bilingual service, the Cruce TransAndino, offered by LS Travel, San José 130 (tel. 65/232424; www.lstravel.com), takes visitors to Bariloche, leaving at 9:30am, stopping for a swim at the Termas Puyehue, passing through Villa la Angostura and on to Bariloche. The tour agency has an office in Bariloche at Mitre 83 (tel. 02944/434111). The cost is $130 (£87) per person, with a minimum two guests (cheaper prices can be had for groups), and includes entrance fees and lunch.
By Car -- Termas de Puyehue is about 75km (47 miles) east from Osorno via Rte. 215. The border with Argentina, Control Fronterizo Cardenal Antonio Samoré, is open daily November through March from 8am to 9pm, and April through October from 8am to 7pm. The road is a bit curvy, and there are some potholes on the Chilean side, so drive slowly.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.