A cool retreat just 5 minutes from the Pantheon, secluded in a maze of small alleyways, the Adriano occupies an elegant 17th-century building, with cozy common areas and modern design. The very hip Gin Corner bar specializes guessed it...with more than 100 types of gin and a menu of custom cocktails. Dripping with atmosphere, the hotel is a welcome find in the middle of the centro storico. Both traditional and apartment-style "annex" rooms are available; be sure to email the hotel for the best rates because it will beat the online sellers.