Although ferries connect Piraeus to Samos, the trip is long. The best way to get here is to fly.
By Plane -- Both Olympic Air and Aegean Airlines offer several flights daily between Athens and Samos. Contact Olympic Air in Athens (tel. 210/966-6666; www.olympicair.com). Contact Aegean Airlines (tel. 801/112-0000; www.aegeanair.com). Athens Airways (www.athensairways.com) has also been listing some flights to Samos. The Samos airport is 3km (2 miles) from Pithagorio, on the road to Ireon; from the airport, you can take a taxi to Vathi (30€) or Pithagorio (20€).
By Boat -- The principal port of Samos is Vathi, also called Samos; the other two ports are Karlovasi and Pithagorio. Ferries from the Cyclades usually stop at both Vathi and Karlovasi: Take care not to get off at the wrong port! There are daily boats (sometimes two) from Piraeus to Karlovasi (11-14 hr.) and Vathi (8-14 hr.); in the opposite direction, ferries travel daily or nearly daily from Samos to Mykonos (5 1/2 hr.). Boats to Hios from Vathi via Karlovasi (5 hr.) travel three times per week; there is also a once-weekly Rhodes-Vathi-Lesvos-Alexandroupoli run. Boats (mostly hydrofoils) to the Dodecanese islands depart regularly from Vathi and Pithagorio. If you want to travel one-way to Turkey, Turkish ferries depart daily (Apr-Oct; less regular off-season); a visa is required for all American, Canadian, British, and Irish citizens who intend to stay for more than 1 day. Be sure to inquire in advance about current visa regulations with a local travel agency.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.