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This San Luis Obispo hotel is just off US-101. It serves breakfast every morning and features an outdoor pool and modern fitness center. Free Wi-Fi is available throughout the hotel. Decorated in warm shades of red and coral, rooms at Holiday Inn Express San Luis Obispo have cable TV and a refrigerator. Other helpful amenities include a work desk and an iron. Guests at the San Luis Obispo Holiday Inn can relax in the hotel’s jacuzzi or get some work done in the well-equipped business center. The front desk is open 24-hours a day. Holiday Inn Express San Luis Obispo is less than a mile from California Polytechnic State University. Old Mission San Luis Obispo is a 4-minute drive away.