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If you've come to quiet Pyrgos for nightlife, you've made a serious mistake—but the action of Fira is only 6km/1mi away. On the other hand, if you've come here for tranquility, a glimpse of village life, and wonderful night skies, you're in the right place. Reached up an impressive (and challenging) flight of steps on one of the island's highest peaks, this boutique hotel belongs to the luxury Relais and Chateaux group. The Zannos Melathron began life in the 19th century as the mansion of a wealthy local family, and today it has a pool, as well as rooms with spa tubs. The painted ceilings and ornate wooden furniture are reminiscent of the mansion's good old days. The hotel has its own restaurant, but with Selene just steps away, you will probably want to eat here only for breakfast and snacks. Check the website for price specials.