Corfu town definitely has a nightlife scene, though many people are content to linger over dinner and then, after a promenade, repair to one of the cafes at the Liston, such as the Capri, Liston, Europa, or Aegli -- all of which have similar selections of light refreshments and drinks. (Treat yourself to the fresh fruit salad at the Aegli!) Others are drawn to the cafes at the north end of the Esplanade, just outside the Liston -- Cafe Bar 92, Magnet, or Cool Down. For a special treat, ascend to the rooftop cafe/bar at Cavalieri hotel. Another choice is Lindos Cafe, overlooking the beach and facilities of the Nautical Club of Corfu. It's approached by steps leading off Leoforos Demokratias, just south and outside the Esplanade. And one of the best-kept secrets of Corfu town is the little Art Cafe, to the right and behind the Museum of Asian Art; its garden provides a wonderful, cool, quiet retreat from the hustle and bustle of the rest of the town.
If you enjoy more action -- loud music and dancing -- several nightspots are along the coast to the north, between Corfu town and the beach resort of Gouvia. They include Ekati, a typical Greek nightclub; Esperides, featuring Greek music; and Corfu by Night, definitely touristy. Be prepared to drop money at these places.
The youngest night crawlers find places that go in and out of favor (and business) from year to year. Among the more enduring up around the Esplanade are the relatively sedate Aktaion, just to the right of the Old Fort; and clubs featuring the latest music such as Hook and Base along Kapodistriou (before the Cavialieri Hotel). Young people seeking more excitement go down past the new port to a strip of flashy discos -- Au Bar, Cristal, Elxis, Privilege. These clubs charge a cover (about 10€/$13, including one drink).
In summer, frequent concerts by orchestras and bands are held on the Esplanade; most of them are free. Corfu town boasts the oldest band in Greece. The Sound-and-Light performances are described in the listing for the Old Fort. September brings Corfu Festival, with concerts, ballet, opera, and theater performances by a mix of Greek and international companies. Carnival is celebrated on the last Sunday before Lent with a parade and the burning of an effigy representing the spirit of Carnival.
Still another possibility would be to take one of the boat cruises that go out each night and provide both a refreshing atmosphere and a view of the glittering island. Any travel agency will be able to sign you up for one of these.
For those who like to gamble, the casino at the Corfu Holiday Palace is a few miles outside of town. Open nightly (8pm-3am) to individuals 23 years or older, it may not have the glamour of Monte Carlo, but it attracts an international set during the high season.
