A dramatic change of pace from Assisi’s heavily medieval aura is in full force at this contemporary redo of a centuries-old convent. Handsome guest quarters have all white surfaces and bursts of bright colors, accented with stone walls and arches, and boldly turned out with Eames chairs, laminate tables, and high-tech lighting. A two-level suite with a hanging sleeping loft is focused on a massive 13th-century fresco of saints in the wilderness, bound to instill nighttime visions. A lavish breakfast buffet and other meals are served in a stark, white-vaulted, high-tech version of the refectory, and downstairs are hedonistic pleasures the former tenants could never have dreamed of—two pools, a series of saunas and steam rooms, and a state-of-the-art spa.