This Michelin-starred temple of gastronomy is perched atop a 12th-century stone edifice—complete with 15th-century frescoes—just next door to the Palais des Papes. Avignon-born Chef Guilhem Sevin is wildly innovative, and many of his dishes have more than a hint of molecular influence. A variety of fixed-price menus are available to choose from and change seasonally. Restaurant Christian Etienne also boasts an impressive wine list.