A pleasing mix of the traditional and the modern prevails at this backstreet guesthouse named after a famous former resident: The creator of the Baptistery’s “Gates of Paradise” had workshops on the top floor of the palazzo. Rooms have plenty of space, with herringbone terracotta floors, whitewashed walls, and high, painted wood ceilings in a vaguely Renaissance style. There is a sauna and Jacuzzi for communal use, so you can soak away the aches and pains of a day’s sightseeing; memory-foam mattresses should help with that, too. E-mail direct if you want to bag the best room rate.