Aqua Expeditions has blown the old concept of creaky, uncomfortable Amazon river cruises out of the water. Its luxury river cruises are aboard the gorgeous, modern 130-foot M.V. Aqua, designed by the well-known Peruvian architect Jordi Puig, and the menu is overseen by a fashionable Lima chef, Miguel Schiaffino. Sleeping quarters are sleekly contemporary, with swank indoor and outdoor lounge spaces, 12 air-conditioned rooms with high-quality bedding, and large, panoramic windows that make it look like you're watching a big-screen movie of the Amazon. Cruises depart from Iquitos and go through the Pacaya-Samiria National Reserve.