Rarely visited, this church and its attached convent hide a fine collection of artwork by some prominent Italian Renaissance artists. The church was built between the end of the 16th century and the beginning of the 17th. Among the masterpieces you'll find inside are in the counterfacade, a fresco by Luca Giordano; in the first chapel to the right, Sant'Alessandro Moribondo by Pietro da Cortona; in the transept, frescoes by Francesco Solimena and statues by Pietro Bernini; and over the altar in the sacristy, the painting San Giovanni Battista, by Guido Reni.

In the annexed Casa dei Padri dell'Oratorio (entrance on Via Duomo 142), you can visit the beautiful Chiostro Maggiore and the Quadreria dei Girolamini, a rich collection of paintings donated to the convent and including notable artists such as Cavalier d'Arpino, Sermoneta, Guido Reni, and Jusepe de Ribera. You can also visit the splendid library, with its beautiful halls that include the beautiful Sala Grande.