Nashville’s 21c is an art-filled escape from the hustle of downtown; it keeps you in the middle of the action (you’re right next to Printers Alley and blocks from Broadway) while letting you get away from it when you want. Showcasing more than 10,500 square feet of exhibition space, rotating installations in the free ground-level galleries reflect global culture. Guest rooms have plush beds and contemporary furnishings offset by large windows. Comforting touches include fluffy robes and Malin + Goetz bath amenities so you can soak off your day. Also inside the hotel you’ll find the Gray & Dudley restaurant, which offers twists on Southern classics that are upscale enough to be interesting but without veering into fussy territory. To wit: the warm chocolate chip cookies, baked to order, which come topped with crunchy sea salt and homemade ice cream. Having them delivered to your room after a cold Nashville night is the coziest of winter warmups.