For our money, this is the place to have your blow-the-vacation-budget meal in Rome. This prestigious Michelin-starred restaurant is a feast for the eyes and the taste buds, with minimalistic decor and astonishingly inventive cooking. Chef Roy Caceres, a native of Colombia, likes to tell a story with each beautifully crafted dish, from exquisite risotto and pasta preparations to elegant meat and fish interpretations. Be prepared for memorable items like fish soup ravioli, “encased” risotto with mushrooms and hazelnut, or lamb with red mole sauce and chia seeds. Tasting menus are full of delightful surprises, and the artistry of the presentations is jaw-dropping.