By Bus -- To Urubamba (1 1/2-2 hr. from Cusco), you can go either via Pisac or via Chinchero (a slightly more direct route). Buses, or combis (S/5), depart from Av. Grau s/n, Cdra. 1, in Cusco and arrive at Terminal Terrestre (no phone), the main bus terminal, about a kilometer (1/2 mile) from town on the main road to Ollantaytambo. Buses from the Urubamba terminal depart for Cusco and Chinchero (1 hr.), as well as Ollantaytambo (30 min.). Combis for other points in the Sacred Valley depart from the intersection of the main road at Avenida Castilla. To continue on to Yucay, just a couple of kilometers down the road, catch a mototaxi or a regular taxi in Urubamba or a colectivo along the highway (headed east, the opposite direction of the bus terminal from town).
By Taxi -- From Cusco, you can catch a cab to Urubamba for about S/70. Shared cars in Cusco leave from Calle Pavitos 567 for Urubamba; they charge just S/10 per person and take about an hour. If you're headed directly to the Valley upon arrival in Cusco, have your hotel arrange for pickup at the airport. If it's a market day, you can easily arrange for the driver to take you to Pisac or Chinchero for a brief stopover along the way. For taxi or minivan trips around the Valley, try Roberto Angles Ochoa (tel. 084/984-752-565).
You should pick up information on the Sacred Valley before leaving Cusco, at the main Tourist Information Office, Mantas 117-A, a block from the Plaza de Armas (tel. 084/263-176); iPerú Av. El Sol 103, Of. 102 (tel. 084/252-974), or from Cusco's South American Explorers Club (tel. 084/245-484). In Urubamba, you might be able to scare up some limited assistance at Av. Cabo Conchatupa s/n; in Yucay, try the office of Turismo Participativo, Plaza Manco II 103 (tel. 084/201-099).
Fast Facts -- If you need cash, you'll find ATMs on either side of the main road to Yucay from Urubamba. For medical assistance, go to Centro de Salud, Av. Cabo Conchatupa s/n (tel. 084/201-334), or Hospital del Instituto Peruano de Seguridad Social, Av. 9 de Noviembre s/n (tel. 084/201-032).
Urubamba is the best spot for Internet cabinas in the Sacred Valley region, with a good supply of machines and fast connections all around town. Academia Internet Urubamba (no phone), established with the help of an American exchange student, is 2 blocks northeast of the Plaza de Armas, on the corner of Jirón Belén and Jirón Grau. There are also a couple of Internet cabinas on the main square. If you need a post office in Urubamba, you'll also find one on the Plaza de Armas.