By Plane -- You can fly from Havana to Bayamo on Aerocaribbean (tel. 23/42-3916 in Bayamo, or 7/879-7524 in Havana; www.cubajet.com) on Tuesday and Friday; the fare is CUC$104 one-way. Flights arrive at Aeropuerto Carlos Manuel de Céspedes, Carretera a Holguín (tel. 23/42-7514; airport code BYM), 10km (6 miles) north of the city. By registered taxi, the trip to town is about CUC$5-CUC$8.
By Bus -- Víazul (tel. 23/42-4036 in Bayamo, or 7/881-1413 in Havana; www.viazul.com) is the most convenient mode of transportation for traveling to Bayamo from Havana and Santiago, and major cities in between. On the Trinidad-Santiago de Cuba line, the bus departs Trinidad at 7:40pm and arrives in Bayamo at 4:50am; the fare is CUC$26. Buses from Santiago bound for points west leave at 9am, 3:15pm 7.30pm, 8pm. and 10pm, and stop in Bayamo 2 hours and 10 minutes later; the fare is CUC$7. On the Havana-Santiago line, there are daily departures at 9:30am, 3:15pm, and 10pm; the trip from Havana is roughly 14 hours and costs CUC$44. On the Varadero-Santiago line the bus leaves Varadero at 9:25pm, and arrives at 9:55am, costing CUC$44. Sometimes you're told there are no spaces on the bus by the ticket office in Bayamo; wait to speak to the bus driver, who may tell you that there are seats left.
The main bus terminal for long-distance buses, the Terminal de Omnibuses, is located on the outskirts of downtown, on Carretera Central near Avenida Jesús Rabi, on the road to Holguín. Horse-drawn carriages and unregistered taxis await passengers to ferry them downtown for CUC$3 (far is higher at night).
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.