Trains run hourly between San Remo and Genoa (about 2 hr.). If you’re arriving by train, note that San Remo’s newer underground railway station, built in 2001, is a bit of a hike from the center of town and the old port. Trains from Genoa continue west for another 20 minutes to Ventimiglia on the French border. Some trains continue on into France; at Ventimiglia you can change onto one of the twice-hourly trains across the border to Nice, 50 minutes west.
The fastest driving route in and out of San Remo is Autostrada A10, which follows the coast from the French border (20 min. away) to Genoa (about 45 min. away). The slower coast road, SS1, cuts right through the center of town and is the best option if you are not going very far (Bordighera and Ventimiglia are reached more quickly on the SS1, traffic permitting).
Since the 1950s, the Sanremo Festival (mid- to late February; www.sanremo.rai.it) has been Italy’s premier music fest, sort of an Italian Grammy Awards. It's spread out over several days with live performances by Italian pop stars, international headliners, and plenty of up-and-comers. Hotels up and down the coast (and into France) get booked up months in advance. Call the tourist office to try to score tickets.