There are 13 buses per day to and from Madrid (trip time: 3 1/2-4 1/2 hr.). There are also five buses running daily from Cáceres (45 min.), and six from Badajoz (2 hr.). A one-way ticket from Madrid costs 16€ to 27€; from Cáceres, 3€; and from Badajoz, 10€ to 18€. Trujillo's bus station, Calle Marqués Albayda (tel. 92-732-12-02; www.avanzabus.com), is on the south side of town, on a side street that intersects with Calle de la Encarnación.
Trujillo lies at a network of large and small roads connecting it to Cáceres via the N-521 and to Lisbon and Madrid via the N-V superhighway. Driving time from Madrid is around 4 hours.
The tourist office, on Plaza Mayor (tel. 92-732-26-77; www.ayto-trujillo.com), is open daily 10am to 2pm and 4 to 7pm.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.