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It's one of the best museums in Italy covering American and European art of the 20th century, but you might find the experience a little jarring, given its location in a city so heavily associated with the High Renaissance and the baroque. Nevertheless, art aficionados will find some fascinating work here, and the galleries occupy Peggy Guggenheim’s wonderful former home, the 18th-century Palazzo Venier dei Leoni, right on the Grand Canal. Guggenheim purchased the mansion in 1949 and lived here, on and off, until her death in 1979. Highlights include Picasso’s extremely abstract “Poet,” and his more gentle “On the Beach,” several works by Kandinsky (“Landscape with Red Spots No. 2” and “White Cross”), Miró’s expressionistic “Seated Woman II,” Klee’s mystical “Magic Garden,” and some unsettling works by Max Ernst (“The Kiss,” “Attirement of the Bride”), who was briefly married to Guggenheim in the 1940s. Also look for Magritte’s “Empire of Light,” Dalí’s “Birth of Liquid Desires,” and a couple of gems from Pollock: his early “Moon Woman,” which recalls Picasso, and “Alchemy,” a more typical “poured” painting. The Italian Futurists are also well represented here, with a rare portrait from Modigliani (“Portrait of the Painter Frank Haviland”). Tip: It’s not a good idea to visit the Guggenheim and St. Mark’s on the same day—it’s a fairly long walk between the two. We also don’t advise seeing it on the same day as the Accademia, even though they are only 10 minutes apart; the artistic overload is likely to prove too much for even the most avid art aficionado.