Four Seasons has been in the posh Yorkville neighborhood for decades, but relocated to its new 55-story location in 2012. This is the flagship property for the internationally known Canadian company. This luxurious five-star hotel takes up floors one through 21, above which are residences (the penthouse sold for $28 million). Hotel rooms offer spacious accommodations, floor-to-ceiling windows, down pillows and duvets, thick terrycloth bathrobes, and bathrooms with a soaking tub and separate walk-in shower with TV embedded into the mirror. A loaner i-Pad graces every room (management hopes guests will use it to book treatments at the massive, 30,000-square-foot on-site spa). The same amenities are offered in standard and premium rooms; the difference is the room size and how high up the room is. Throughout the hotel there are fabulous floral arrangements and 1,700 pieces of original Canadian Art, with dandelions a recurring theme. The ninth-floor pool area with whirlpool has large windows overlooking the neighborhood. And a special treat awaits fitness buffs: the on-site gym features virtual reality equipment that can give the illusion of running along the Seattle waterfront or through the European Alps. You may need that extra incentive to run longer as you'll eat very well here: along with a casual bar/restaurant is an outpost of star chef Daniel Boulud's Café Boulud featuring exquisite contemporary and classic French cuisine, 350 wines, and large windows overlooking the Yorkville neighborhood. A prix-fixe lunch menu is available if you want to try if for less money.