The fastest route from San Francisco is via U.S. 101 north to Cloverdale. Then take Hwy. 128 west to Hwy. 1, and then go north along the coast. It's about a 4-hour drive. (You could also take U.S. 101 all the way to Ukiah or Willits and cut over to the west from there.) The most scenic route, if you have the time and your stomach doesn't mind the twists and turns, is to take Hwy. 1 north along the coast the entire way; it's at least a 5- to 6-hour drive.
Note: This information was accurate when it was published, but can change without notice. Please be sure to confirm all rates and details directly with the companies in question before planning your trip.
